Molecular Genetics of Pigment Dispersion Syndrome and Pigmentary Glaucoma: New Insights into Mechanisms
Joint Authors
Lahola-Chomiak, Adrian A.
Walter, Michael
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-26
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
We explore the ideas and advances surrounding the genetic basis of pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG).
As PG is the leading cause of nontraumatic blindness in young adults and current tailored interventions have proven ineffective, a better understanding of the underlying causes of PDS, PG, and their relationship is essential.
Despite PDS being a subclinical disease, a large proportion of patients progress to PG with associated vision loss.
Decades of research have supported a genetic component both for PDS and conversion to PG.
We review the body of evidence supporting a genetic basis in humans and animal models and reevaluate classical mechanisms of PDS/PG considering this new evidence.
American Psychological Association (APA)
Lahola-Chomiak, Adrian A.& Walter, Michael. 2018. Molecular Genetics of Pigment Dispersion Syndrome and Pigmentary Glaucoma: New Insights into Mechanisms. Journal of Ophthalmology،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1196725
Modern Language Association (MLA)
Lahola-Chomiak, Adrian A.& Walter, Michael. Molecular Genetics of Pigment Dispersion Syndrome and Pigmentary Glaucoma: New Insights into Mechanisms. Journal of Ophthalmology No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1196725
American Medical Association (AMA)
Lahola-Chomiak, Adrian A.& Walter, Michael. Molecular Genetics of Pigment Dispersion Syndrome and Pigmentary Glaucoma: New Insights into Mechanisms. Journal of Ophthalmology. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1196725
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1196725