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Markers and Biomarkers of Endothelium: When Something Is Rotten in the State
Joint Authors
Goncharov, Nikolay V.
Nadeev, Alexander D.
Jenkins, Richard O.
Avdonin, Pavel V.
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-27, 27 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-23
Country of Publication
Egypt
No. of Pages
27
Main Subjects
Abstract EN
Endothelium is a community of endothelial cells (ECs), which line the blood and lymphatic vessels, thus forming an interface between the tissues and the blood or lympha.
This strategic position of endothelium infers its indispensable functional role in controlling vasoregulation, haemostasis, and inflammation.
The state of endothelium is simultaneously the cause and effect of many diseases, and this is coupled with modifications of endothelial phenotype represented by markers and with biochemical profile of blood represented by biomarkers.
In this paper, we briefly review data on the functional role of endothelium, give definitions of endothelial markers and biomarkers, touch on the methodological approaches for revealing biomarkers, present an implicit role of endothelium in some toxicological mechanistic studies, and survey the role of reactive oxygen species (ROS) in modulation of endothelial status.
American Psychological Association (APA)
Goncharov, Nikolay V.& Nadeev, Alexander D.& Jenkins, Richard O.& Avdonin, Pavel V.. 2017. Markers and Biomarkers of Endothelium: When Something Is Rotten in the State. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-27.
https://search.emarefa.net/detail/BIM-1196730
Modern Language Association (MLA)
Goncharov, Nikolay V.…[et al.]. Markers and Biomarkers of Endothelium: When Something Is Rotten in the State. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-27.
https://search.emarefa.net/detail/BIM-1196730
American Medical Association (AMA)
Goncharov, Nikolay V.& Nadeev, Alexander D.& Jenkins, Richard O.& Avdonin, Pavel V.. Markers and Biomarkers of Endothelium: When Something Is Rotten in the State. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-27.
https://search.emarefa.net/detail/BIM-1196730
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1196730