From DMEK to Corneal Endothelial Cell Therapy: Technical and Biological Aspects
Joint Authors
Nuzzi, Raffaele
Tridico, Federico
Marolo, Paola
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The main treatment available for restoration of the corneal endothelium is keratoplasty and DMEK provides faster visual recovery and better postoperative visual acuity when compared to DSAEK.
However, the technical challenges related to this technique and the steep technical learning curve seem to prevent the overcoming of DSAEK in favor of DMEK.
Furthermore, the outcome of lamellar keratoplasty techniques is influenced by problems related to corneal grafting tissue availability, management, and quality.
On the other hand, improvements in the field of cell engineering have opened the way for the use of stem cells-derived corneal endothelial cells with regenerative intent.
In this overview, latest findings in endothelial cell engineering are reported, and perspectives of clinical application of mesenchymal stem cells for corneal endothelial replacement and regeneration are evaluated.
American Psychological Association (APA)
Nuzzi, Raffaele& Marolo, Paola& Tridico, Federico. 2018. From DMEK to Corneal Endothelial Cell Therapy: Technical and Biological Aspects. Journal of Ophthalmology،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1196790
Modern Language Association (MLA)
Nuzzi, Raffaele…[et al.]. From DMEK to Corneal Endothelial Cell Therapy: Technical and Biological Aspects. Journal of Ophthalmology No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1196790
American Medical Association (AMA)
Nuzzi, Raffaele& Marolo, Paola& Tridico, Federico. From DMEK to Corneal Endothelial Cell Therapy: Technical and Biological Aspects. Journal of Ophthalmology. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1196790
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1196790