Ocular Manifestations of Alzheimer’s and Other Neurodegenerative Diseases: The Prospect of the Eye as a Tool for the Early Diagnosis of Alzheimer’s Disease
Joint Authors
Pintor, Jesús
Pérez de Lara, María Jesús
Colligris, Pade
Colligris, Basilio
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-30
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Dementia, including Alzheimer’s disease (AD), is a major disorder, leading to several ocular manifestations amongst the elderly population.
These visual disorders may be due to retinal nerve degenerative changes, including nerve fibre layer thinning, degeneration of retinal ganglion cells, and changes to vascular parameters.
There is no cure for Alzheimer’s, but medicines can slow down the development of many of the classic symptoms, such as loss of memory and communication skills, mood swings, and depression.
The disease diagnosis is difficult, and it is only possible through PET scans of the brain, detecting evidence of the accumulation of amyloid and tau.
PET is expensive and invasive, requiring the injection of radioactive tracers, which bind with these proteins and glow during scanning.
Recently, scientists developed promising eye-scan techniques that may detect Alzheimer’s disease at its earliest stage, before major symptoms appear, leading to improved management of the disease symptoms.
In this review, we are discussing the visual abnormalities of Alzheimer’s and other neurodegenerative diseases, focused on ocular functional-visual-structural biomarkers, retinal pathology, and potential novel diagnostic tools.
American Psychological Association (APA)
Colligris, Pade& Pérez de Lara, María Jesús& Colligris, Basilio& Pintor, Jesús. 2018. Ocular Manifestations of Alzheimer’s and Other Neurodegenerative Diseases: The Prospect of the Eye as a Tool for the Early Diagnosis of Alzheimer’s Disease. Journal of Ophthalmology،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1197009
Modern Language Association (MLA)
Colligris, Pade…[et al.]. Ocular Manifestations of Alzheimer’s and Other Neurodegenerative Diseases: The Prospect of the Eye as a Tool for the Early Diagnosis of Alzheimer’s Disease. Journal of Ophthalmology No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1197009
American Medical Association (AMA)
Colligris, Pade& Pérez de Lara, María Jesús& Colligris, Basilio& Pintor, Jesús. Ocular Manifestations of Alzheimer’s and Other Neurodegenerative Diseases: The Prospect of the Eye as a Tool for the Early Diagnosis of Alzheimer’s Disease. Journal of Ophthalmology. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1197009
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1197009