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Peripapillary Vessel Density Reversal after Trabeculectomy in Glaucoma
Joint Authors
In, Jung Hee
Lee, So Yeon
Cho, Seok Ho
Hong, Young Jae
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To evaluate the microvascular changes at the peripapillary area and optic disc in glaucomatous eyes after IOP lowering by trabeculectomy using OCT angiography.
Methods.
25 patients with primary open-angle glaucoma (POAG) who underwent trabeculectomy by a single surgeon were evaluated.
Using optical coherence tomography angiography, vessel density was evaluated within the whole image, peripapillary, nasal region, and temporal region.
Peripapillary vessel density was measured preoperative, 1 week, 1 month, and 3 months postoperatively in POAG patients.
Reversal of vessel density was calculated for all analyzed areas.
Results.
The intraocular pressure (IOP) decreased from 30.92 ± 6.32 mmHg (range, 18–44) to 12.64 ± 3.35 mmHg (range, 8–22) at 3-month postoperatively.
Compared with the preoperative baseline value, whole vessel density, peripapillary vessel density (PvD), and PvD in nasal region and temporal region were significantly increased at 3-month postoperatively.
The magnitude of the vessel density reversal was significantly associated with higher preoperative IOP and greater IOP reduction.
Conclusions.
A significant increase in the peripapillary vessel density was demonstrated after trabeculectomy using OCT angiography.
The reversal of peripapillary vessel density was associated with higher preoperative IOP and greater IOP reduction.
Our postoperative results suggest that the ocular perfusion impairment by high intraocular pressure can be improved by IOP reduction, and the reversal of microvasculature may contribute to the rate of glaucoma progression.
American Psychological Association (APA)
In, Jung Hee& Lee, So Yeon& Cho, Seok Ho& Hong, Young Jae. 2018. Peripapillary Vessel Density Reversal after Trabeculectomy in Glaucoma. Journal of Ophthalmology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1197050
Modern Language Association (MLA)
In, Jung Hee…[et al.]. Peripapillary Vessel Density Reversal after Trabeculectomy in Glaucoma. Journal of Ophthalmology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1197050
American Medical Association (AMA)
In, Jung Hee& Lee, So Yeon& Cho, Seok Ho& Hong, Young Jae. Peripapillary Vessel Density Reversal after Trabeculectomy in Glaucoma. Journal of Ophthalmology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1197050
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1197050