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Deep Brain Stimulation in Parkinson’s Disease: New and Emerging Targets for Refractory Motor and Nonmotor Symptoms
Joint Authors
Anderson, Dustin
Beecher, Grayson
Ba, Fang
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-06
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Parkinson’s disease (PD) is a progressive neurodegenerative condition characterized by bradykinesia, tremor, rigidity, and postural instability (PI), in addition to numerous nonmotor manifestations.
Many pharmacological therapies now exist to successfully treat PD motor symptoms; however, as the disease progresses, it often becomes challenging to treat with medications alone.
Deep brain stimulation (DBS) has become a crucial player in PD treatment, particularly for patients who have disabling motor complications from medical treatment.
Well-established DBS targets include the subthalamic nucleus (STN), the globus pallidus pars interna (GPi), and to a lesser degree the ventral intermediate nucleus (VIM) of the thalamus.
Studies of alternative DBS targets for PD are ongoing, the majority of which have shown some clinical benefit; however, more carefully designed and controlled studies are needed.
In the present review, we discuss the role of these new and emerging DBS targets in treating refractory axial motor symptoms and other motor and nonmotor symptoms (NMS).
American Psychological Association (APA)
Anderson, Dustin& Beecher, Grayson& Ba, Fang. 2017. Deep Brain Stimulation in Parkinson’s Disease: New and Emerging Targets for Refractory Motor and Nonmotor Symptoms. Parkinson’s Disease،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1197064
Modern Language Association (MLA)
Anderson, Dustin…[et al.]. Deep Brain Stimulation in Parkinson’s Disease: New and Emerging Targets for Refractory Motor and Nonmotor Symptoms. Parkinson’s Disease No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1197064
American Medical Association (AMA)
Anderson, Dustin& Beecher, Grayson& Ba, Fang. Deep Brain Stimulation in Parkinson’s Disease: New and Emerging Targets for Refractory Motor and Nonmotor Symptoms. Parkinson’s Disease. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1197064
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1197064