Earlier Intervention with Deep Brain Stimulation for Parkinson’s Disease
Joint Authors
Suarez-Cedeno, Gerson
Suescun, Jessika
Schiess, Mya C.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-16
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Neuromodulation of subcortical areas of the brain as therapy to reduce Parkinsonian motor symptoms was developed in the mid-twentieth century and went through many technical and scientific advances that established specific targets and stimulation parameters.
Deep Brain Stimulation (DBS) was approved by the FDA in 2002 as neuromodulation therapy for advanced Parkinson’s disease, prompting several randomized controlled trials that confirmed its safety and effectiveness.
The implantation of tens of thousands of patients in North America and Europe ignited research into its potential role in early disease stages and the therapeutic benefit of DBS compared to best medical therapy.
In 2013 the EARLY-STIM trial provided Class I evidence for the use of DBS earlier in Parkinson’s disease.
This finding led to the most recent FDA approval in patients with at least 4 years of disease duration and 4 months of motor complications as an adjunct therapy for patients not adequately controlled with medications.
This following review highlights the historical development and advances made overtime in DBS implantation, the current application, and the challenges that come with it.
American Psychological Association (APA)
Suarez-Cedeno, Gerson& Suescun, Jessika& Schiess, Mya C.. 2017. Earlier Intervention with Deep Brain Stimulation for Parkinson’s Disease. Parkinson’s Disease،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1197162
Modern Language Association (MLA)
Suarez-Cedeno, Gerson…[et al.]. Earlier Intervention with Deep Brain Stimulation for Parkinson’s Disease. Parkinson’s Disease No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1197162
American Medical Association (AMA)
Suarez-Cedeno, Gerson& Suescun, Jessika& Schiess, Mya C.. Earlier Intervention with Deep Brain Stimulation for Parkinson’s Disease. Parkinson’s Disease. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1197162
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1197162