New Transcriptional Reporters to Quantify and Monitor PPARγ Activity
Joint Authors
Fournier, Thierry
Degrelle, Séverine A.
Shoaito, Hussein
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The peroxisome-proliferator-activated-receptor-γ (PPARγ) is a member of the nuclear receptor superfamily that plays a critical role in diverse biological processes, including adipogenesis, lipid metabolism, and placental development.
To study the activity of PPARγ, we constructed two new reporter genes: a fluorescent GFP-tagged histone-2B (PPRE-H2B-eGFP) and a secreted nanoluciferase (PPRE-pNL1.3[secNluc]).
This study demonstrates their usage to monitor PPARγ activity in different cell types and screen for PPARγ’s potential ligands.
American Psychological Association (APA)
Degrelle, Séverine A.& Shoaito, Hussein& Fournier, Thierry. 2017. New Transcriptional Reporters to Quantify and Monitor PPARγ Activity. PPAR Research،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1197252
Modern Language Association (MLA)
Degrelle, Séverine A.…[et al.]. New Transcriptional Reporters to Quantify and Monitor PPARγ Activity. PPAR Research No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1197252
American Medical Association (AMA)
Degrelle, Séverine A.& Shoaito, Hussein& Fournier, Thierry. New Transcriptional Reporters to Quantify and Monitor PPARγ Activity. PPAR Research. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1197252
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1197252
