The Effect of Tobacco Smoking on Bone Mass: An Overview of Pathophysiologic Mechanisms
Joint Authors
AL-Bashaireh, Ahmad M.
Haddad, Linda G.
Kelly, Debra Lynch
Chengguo, Xing
Yoon, Saunjoo
Weaver, Michael
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-02
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Recent evidence demonstrates that tobacco smoking causes an imbalance in bone turnover, leading to lower bone mass and making bone vulnerable to osteoporosis and fracture.
Tobacco smoke influences bone mass indirectly through alteration of body weight, parathyroid hormone-vitamin D axis, adrenal hormones, sex hormones, and increased oxidative stress on bony tissues.
Also, tobacco smoke influences bone mass through a direct effect on osteogenesis and angiogenesis of bone.
A RANKL-RANK-OPG pathway is an essential regulatory pathway for bone metabolism and its importance lies in its interaction with most of the pathophysiologic mechanisms by which smoking influences bone mass.
Both first- and secondhand smoke adversely affect bone mass; smoking cessation seems to reverse the effect of smoking and improve bone health.
Recent advances in research on bone turnover markers could advance scientific knowledge regarding the mechanisms by which smoking may influence bone mass.
American Psychological Association (APA)
AL-Bashaireh, Ahmad M.& Haddad, Linda G.& Weaver, Michael& Chengguo, Xing& Kelly, Debra Lynch& Yoon, Saunjoo. 2018. The Effect of Tobacco Smoking on Bone Mass: An Overview of Pathophysiologic Mechanisms. Journal of Osteoporosis،Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1197298
Modern Language Association (MLA)
AL-Bashaireh, Ahmad M.…[et al.]. The Effect of Tobacco Smoking on Bone Mass: An Overview of Pathophysiologic Mechanisms. Journal of Osteoporosis No. 2018 (2018), pp.1-17.
https://search.emarefa.net/detail/BIM-1197298
American Medical Association (AMA)
AL-Bashaireh, Ahmad M.& Haddad, Linda G.& Weaver, Michael& Chengguo, Xing& Kelly, Debra Lynch& Yoon, Saunjoo. The Effect of Tobacco Smoking on Bone Mass: An Overview of Pathophysiologic Mechanisms. Journal of Osteoporosis. 2018. Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1197298
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1197298