Study of Endothelio- and Osteoprotective Effects of Combination of Rosuvastatin with L-Norvaline in Experiment

Joint Authors

Faitelson, A. V.
Sobolev, M. S.
Anikanov, A. V.
Koklina, N. U.
Chernomortseva, E. S.
Dubrovin, G. M.
Gudyrev, O. S.
Rajkumar, D. S. R.

Source

Journal of Osteoporosis

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-11-05

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases
Medicine

Abstract EN

The experiment was carried out on 120 female white Wistar rats, to study the endothelio- and osteoprotective action of the combination of rosuvastatin with L-norvaline in the model of experimental osteoporosis.

It was found that, after ovariectomy in rats, endothelial dysfunction of the vessels of the microcirculatory bed of bone tissue develops, leading to the appearance of osteoporosis, but the combination of the studied drugs prevents the decrease in the level of microcirculation in the bone tissue, thereby preventing the thinning of bone trabeculae and preventing the occurrence of microfractures in them.

American Psychological Association (APA)

Sobolev, M. S.& Faitelson, A. V.& Gudyrev, O. S.& Rajkumar, D. S. R.& Dubrovin, G. M.& Anikanov, A. V.…[et al.]. 2018. Study of Endothelio- and Osteoprotective Effects of Combination of Rosuvastatin with L-Norvaline in Experiment. Journal of Osteoporosis،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1197300

Modern Language Association (MLA)

Sobolev, M. S.…[et al.]. Study of Endothelio- and Osteoprotective Effects of Combination of Rosuvastatin with L-Norvaline in Experiment. Journal of Osteoporosis No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1197300

American Medical Association (AMA)

Sobolev, M. S.& Faitelson, A. V.& Gudyrev, O. S.& Rajkumar, D. S. R.& Dubrovin, G. M.& Anikanov, A. V.…[et al.]. Study of Endothelio- and Osteoprotective Effects of Combination of Rosuvastatin with L-Norvaline in Experiment. Journal of Osteoporosis. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1197300

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1197300