![](/images/graphics-bg.png)
Effects of Addition of Preoperative Intravenous Ibuprofen to Pregabalin on Postoperative Pain in Posterior Lumbar Interbody Fusion Surgery
Joint Authors
Pınar, Hüseyin Ulaş
Karaca, Ömer
Karakoç, Fatma
Doğan, Rafi
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
Ibuprofen and pregabalin both have independent positive effects on postoperative pain.
The aim of the study is researching effect of 800 mg i.v.
ibuprofen in addition to preoperative single dose pregabalin on postoperative analgesia and morphine consumption in posterior lumbar interbody fusion surgery.
Materials and Methods.
42 adult ASA I-II physical status patients received 150 mg oral pregabalin 1 hour before surgery.
Patients received either 250 ml saline with 800 mg i.v.
ibuprofen or saline without ibuprofen 30 minutes prior to the surgery.
Postoperative analgesia was obtained by morphine patient controlled analgesia (PCA) and 1 g i.v.
paracetamol every six hours.
PCA morphine consumption was recorded and postoperative pain was evaluated by Visual Analog Scale (VAS) in postoperative recovery room, at the 1st, 2nd, 4th, 8th, 12th, 24th, 36th, and 48th hours.
Results.
Postoperative pain was significantly lower in ibuprofen group in recovery room, at the 1st, 2nd, 36th, and 48th hours.
Total morphine consumption was lower in ibuprofen group at the 2nd, 4th, 8th, 12th, and 48th hours.
Conclusions.
Multimodal analgesia with preoperative ibuprofen added to preoperative pregabalin safely decreases postoperative pain and total morphine consumption in patients having posterior lumbar interbody fusion surgery, without increasing incidences of bleeding or other side effects.
American Psychological Association (APA)
Pınar, Hüseyin Ulaş& Karaca, Ömer& Karakoç, Fatma& Doğan, Rafi. 2017. Effects of Addition of Preoperative Intravenous Ibuprofen to Pregabalin on Postoperative Pain in Posterior Lumbar Interbody Fusion Surgery. Pain Research and Management،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1197320
Modern Language Association (MLA)
Pınar, Hüseyin Ulaş…[et al.]. Effects of Addition of Preoperative Intravenous Ibuprofen to Pregabalin on Postoperative Pain in Posterior Lumbar Interbody Fusion Surgery. Pain Research and Management No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1197320
American Medical Association (AMA)
Pınar, Hüseyin Ulaş& Karaca, Ömer& Karakoç, Fatma& Doğan, Rafi. Effects of Addition of Preoperative Intravenous Ibuprofen to Pregabalin on Postoperative Pain in Posterior Lumbar Interbody Fusion Surgery. Pain Research and Management. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1197320
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1197320