Epidemiology of Rotavirus A in Nigeria: Molecular Diversity and Current Insights
Joint Authors
Faneye, Adedayo Omotayo
Adeniji, Johnson Adekunle
Motayo, Babatunde O.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Rotavirus induced acute gastroenteritis AGE has been a major disease burden in Nigeria, since it was first reported in 1985.
Prevalence rates have increased with severe public health consequences particularly among children.
The vaccine Rotarix® has been introduced and is commercially available in Nigeria.
However routine rotavirus vaccination is yet to be introduced into the National Immunization Program.
Molecular epidemiology of rotavirus in Nigeria has shown the presence of various genotypes, with genotype G12P [ 8 ] being the most recent introduction.
There are however gaps in molecular data on rotavirus in Nigeria.
We therefore reviewed molecular data on rotavirus isolated in Nigeria and also analyzed VP4 and VP7 genes of Nigerian rotavirus strains in Genbank.
We have shown that there is a distinct trend in rotavirus molecular epidemiology in Nigeria, with new genotype introductions occurring after the year 2010.
We also observed from our analysis the emergence of genotype G12 Lineage III as a dominant genotype.
This information elucidates rotavirus molecular epidemiology in Nigeria and gives insight to the expanding landscape of rotavirus genotypes.
We recommend the institution of molecular surveillance country wide, before considering the inclusion of rotavirus vaccination into the National Immunization Program in Nigeria, in other to monitor evolution of divergent or recombinant strains.
American Psychological Association (APA)
Motayo, Babatunde O.& Faneye, Adedayo Omotayo& Adeniji, Johnson Adekunle. 2018. Epidemiology of Rotavirus A in Nigeria: Molecular Diversity and Current Insights. Journal of Pathogens،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1197502
Modern Language Association (MLA)
Motayo, Babatunde O.…[et al.]. Epidemiology of Rotavirus A in Nigeria: Molecular Diversity and Current Insights. Journal of Pathogens No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1197502
American Medical Association (AMA)
Motayo, Babatunde O.& Faneye, Adedayo Omotayo& Adeniji, Johnson Adekunle. Epidemiology of Rotavirus A in Nigeria: Molecular Diversity and Current Insights. Journal of Pathogens. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1197502
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1197502