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Preoperative Factors Associated with Infiltrative Histologic Growth Patterns in Extremity Soft Tissue Sarcoma
Joint Authors
Han, I.
Lee, Cheol
Park, Jong Woong
Kim, Han-Soo
Yoo, Hye Jin
Yun, Ji Yeon
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Soft tissue sarcoma (STS) with an infiltrative histologic growth pattern, when compared to STS with an expansile pattern, may pose difficulties in local control.
Preoperative assessment of the presence of infiltrative histologic growth pattern would be helpful in deciding treatment strategies.
A review of 144 patients who underwent surgery for extremity STS was performed.
Microscopically, the histologic growth pattern was defined as infiltrative if the penetration of the tumor cells into the surrounding tissue was observed.
Possible clinicopathologic factors that might be associated with infiltrative histologic growth pattern were investigated with regard to patient demographics, tumor characteristics, and MRI findings.
Of the 144 tumors, 71 (49%) showed infiltrative histologic growth pattern.
On multivariate analysis, histological subtypes other than liposarcoma (OR = 4.57, p=0.02) and infiltrative border on MRI (OR = 2.48, p=0.01) were independent factors associated with infiltrative histologic growth pattern.
Predictive index based on these two factors showed a significant improved accuracy (ROC-AUC = 0.647) for predicting infiltrative histologic growth pattern compared to either factor alone.
Our data suggests that liposarcoma histology and tumor border on MRI can predict histologic growth pattern in extremity STS.
American Psychological Association (APA)
Park, Jong Woong& Kim, Han-Soo& Lee, Cheol& Yoo, Hye Jin& Yun, Ji Yeon& Han, I.. 2017. Preoperative Factors Associated with Infiltrative Histologic Growth Patterns in Extremity Soft Tissue Sarcoma. Complexity،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1197730
Modern Language Association (MLA)
Park, Jong Woong…[et al.]. Preoperative Factors Associated with Infiltrative Histologic Growth Patterns in Extremity Soft Tissue Sarcoma. Complexity No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1197730
American Medical Association (AMA)
Park, Jong Woong& Kim, Han-Soo& Lee, Cheol& Yoo, Hye Jin& Yun, Ji Yeon& Han, I.. Preoperative Factors Associated with Infiltrative Histologic Growth Patterns in Extremity Soft Tissue Sarcoma. Complexity. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1197730
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1197730