Predictors of Wound Complications following Radiation and Surgical Resection of Soft Tissue Sarcomas
Joint Authors
LeBrun, Drake G.
Guttmann, David M.
Shabason, Jacob E.
Levin, William P.
Kovach, Stephen J.
Weber, Kristy L.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-15
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Wound complications represent a major source of morbidity in patients undergoing radiation therapy (RT) and surgical resection of soft tissue sarcomas (STS).
We investigated whether factors related to RT, surgery, patient comorbidities, and tumor histopathology predict the development of wound complications.
An observational study of patients who underwent STS resection and RT was performed.
The primary outcome was the occurrence of any wound complication up to four months postoperatively.
Significant predictors of wound complications were identified using multivariable logistic regression.
Sixty-five patients representing 67 cases of STS were identified.
Median age was 59 years (range 22–90) and 34 (52%) patients were female.
The rates of major wound complications and any wound complications were 21% and 33%, respectively.
After adjusting for radiation timing, diabetes (OR 9.6; 95% CI 1.4–64.8; P=0.02), grade ≥2 radiation dermatitis (OR 4.8; 95% CI 1.2–19.2; P=0.03), and the use of 3D conformal RT (OR 4.6; 95% CI 1.1–20.0; P=0.04) were associated with an increased risk of any wound complication on multivariable analysis.
These data suggest that radiation dermatitis and radiation modality are predictors of wound complications in patients with STS.
American Psychological Association (APA)
LeBrun, Drake G.& Guttmann, David M.& Shabason, Jacob E.& Levin, William P.& Kovach, Stephen J.& Weber, Kristy L.. 2017. Predictors of Wound Complications following Radiation and Surgical Resection of Soft Tissue Sarcomas. Complexity،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1197732
Modern Language Association (MLA)
LeBrun, Drake G.…[et al.]. Predictors of Wound Complications following Radiation and Surgical Resection of Soft Tissue Sarcomas. Complexity No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1197732
American Medical Association (AMA)
LeBrun, Drake G.& Guttmann, David M.& Shabason, Jacob E.& Levin, William P.& Kovach, Stephen J.& Weber, Kristy L.. Predictors of Wound Complications following Radiation and Surgical Resection of Soft Tissue Sarcomas. Complexity. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1197732
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1197732