Ligament-Derived Stem Cells: Identification, Characterisation, and Therapeutic Application
Joint Authors
Lee, Katie Joanna
Clegg, Peter David
Comerford, Eithne Josephine
Canty-Laird, Elizabeth Gail
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-12
Country of Publication
Egypt
No. of Pages
9
Abstract EN
Ligament is prone to injury and degeneration and has poor healing potential and, with currently ineffective treatment strategies, stem cell therapies may provide an exciting new treatment option.
Ligament-derived stem cell (LDSC) populations have been isolated from a number of different ligament types with the majority of studies focussing on periodontal ligament.
To date, only a few studies have investigated LDSC populations in other types of ligament, for example, intra-articular ligaments; however, this now appears to be a developing field.
This literature review aims to summarise the current information on nondental LDSCs including in vitro characteristics of LDSCs and their therapeutic potential.
The stem cell niche has been shown to be vital for stem cell survival and function in a number of different physiological systems; therefore, the LDSC niche may have an impact on LDSC phenotype.
The role of the LDSC niche on LDSC viability and function will be discussed as well as the therapeutic potential of LDSC niche modulation.
American Psychological Association (APA)
Lee, Katie Joanna& Clegg, Peter David& Comerford, Eithne Josephine& Canty-Laird, Elizabeth Gail. 2017. Ligament-Derived Stem Cells: Identification, Characterisation, and Therapeutic Application. Stem Cells International،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1200859
Modern Language Association (MLA)
Lee, Katie Joanna…[et al.]. Ligament-Derived Stem Cells: Identification, Characterisation, and Therapeutic Application. Stem Cells International No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1200859
American Medical Association (AMA)
Lee, Katie Joanna& Clegg, Peter David& Comerford, Eithne Josephine& Canty-Laird, Elizabeth Gail. Ligament-Derived Stem Cells: Identification, Characterisation, and Therapeutic Application. Stem Cells International. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1200859
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1200859