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An Examination of the Role of Transcriptional and Posttranscriptional Regulation in Rhabdomyosarcoma
Joint Authors
Hron, Alexander J.
Asakura, Atsushi
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-30
Country of Publication
Egypt
No. of Pages
10
Abstract EN
Rhabdomyosarcoma (RMS) is an aggressive family of soft tissue tumors that most commonly manifests in children.
RMS variants express several skeletal muscle markers, suggesting myogenic stem or progenitor cell origin of RMS.
In this review, the roles of both recently identified and well-established microRNAs in RMS are discussed and summarized in a succinct, tabulated format.
Additionally, the subtypes of RMS are reviewed along with the involvement of basic helix-loop-helix (bHLH) proteins, Pax proteins, and microRNAs in normal and pathologic myogenesis.
Finally, the current and potential future treatment options for RMS are outlined.
American Psychological Association (APA)
Hron, Alexander J.& Asakura, Atsushi. 2017. An Examination of the Role of Transcriptional and Posttranscriptional Regulation in Rhabdomyosarcoma. Stem Cells International،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1200991
Modern Language Association (MLA)
Hron, Alexander J.& Asakura, Atsushi. An Examination of the Role of Transcriptional and Posttranscriptional Regulation in Rhabdomyosarcoma. Stem Cells International No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1200991
American Medical Association (AMA)
Hron, Alexander J.& Asakura, Atsushi. An Examination of the Role of Transcriptional and Posttranscriptional Regulation in Rhabdomyosarcoma. Stem Cells International. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1200991
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1200991