Detection of Immunoglobulin E with a Graphene-Based Field-Effect Transistor Aptasensor
Joint Authors
Burke, Peter J.
Lan, Yi
Farid, Sidra
Meshik, Xenia
Xu, Ke
Choi, Min
Ranginwala, Saadia
Wang, Yung Yu
Dutta, Mitra
Stroscio, Michael A.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
DNA aptamers have the ability to bind to target molecules with high selectivity and therefore have a wide range of clinical applications.
Herein, a graphene substrate functionalized with a DNA aptamer is used to sense immunoglobulin E.
The graphene serves as the conductive substrate in this field-effect-transistor-like (FET-like) structure.
A voltage probe in an electrolyte is used to sense the presence of IgE as a result of the changes in the charge distribution that occur when an IgE molecule binds to the IgE DNA-based aptamer.
Because IgE is an antibody associated with allergic reactions and immune deficiency-related diseases, its detection is of utmost importance for biomedical applications.
American Psychological Association (APA)
Lan, Yi& Farid, Sidra& Meshik, Xenia& Xu, Ke& Choi, Min& Ranginwala, Saadia…[et al.]. 2018. Detection of Immunoglobulin E with a Graphene-Based Field-Effect Transistor Aptasensor. Journal of Sensors،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1200992
Modern Language Association (MLA)
Lan, Yi…[et al.]. Detection of Immunoglobulin E with a Graphene-Based Field-Effect Transistor Aptasensor. Journal of Sensors No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1200992
American Medical Association (AMA)
Lan, Yi& Farid, Sidra& Meshik, Xenia& Xu, Ke& Choi, Min& Ranginwala, Saadia…[et al.]. Detection of Immunoglobulin E with a Graphene-Based Field-Effect Transistor Aptasensor. Journal of Sensors. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1200992
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1200992