Acute Phase Neuronal Activity for the Prognosis of Stroke Recovery
Joint Authors
Tecchio, Franca
Rossini, Paolo Maria
Zappasodi, Filippo
Pasqualetti, Patrizio
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-08
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Strokes causing similar lesions and clinical states can be followed by diverse regains of neurological functions, indicating that the clinical recovery can depend on individual modulating factors.
A promising line to disclose these factors, to finally open new therapeutic strategies, is to search for individual indices of recovery prognosis.
Here, we pursued on strengthening the value of acute phase electrophysiological biomarkers for poststroke functional recovery in a wide group of patients.
We enrolled 120 patients affected by a monohemispheric stroke within the middle cerebral artery territory (70 left and 50 right damages) and collected the NIH stroke scale (NIHSS) score in the acute phase (T0, median 4 days) and chronic follow-up (T1, median 6 months).
At T0, we executed electrophysiological noninvasive assessment (19-channel electroencephalography (EEG) or 28 channels per side magnetoencephalography (MEG)) of brain activity at rest by means of band powers in the contra- and ipsilesional hemispheres (CLH, ILH) or the homologous area symmetry (HArS).
Low-band (2-6 Hz) HArS entered the regression model for predicting the stabilized clinical state (p<0.001), with bilateral impairment correlated with a poor outcome.
Present data strengthen the fact that low-band impairment of homologous ipsi- and contralesional hemispheric regions in the acute stroke indicate a negative prognosis of clinical recovery.
American Psychological Association (APA)
Zappasodi, Filippo& Pasqualetti, Patrizio& Rossini, Paolo Maria& Tecchio, Franca. 2019. Acute Phase Neuronal Activity for the Prognosis of Stroke Recovery. Neural Plasticity،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1201036
Modern Language Association (MLA)
Zappasodi, Filippo…[et al.]. Acute Phase Neuronal Activity for the Prognosis of Stroke Recovery. Neural Plasticity No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1201036
American Medical Association (AMA)
Zappasodi, Filippo& Pasqualetti, Patrizio& Rossini, Paolo Maria& Tecchio, Franca. Acute Phase Neuronal Activity for the Prognosis of Stroke Recovery. Neural Plasticity. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1201036
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1201036