Hyperexcitability of Cortical Oscillations in Patients with Somatoform Pain Disorder: A Resting-State EEG Study
Joint Authors
Peng, Weiwei
Ye, Qian
Yan, Dong
Yao, Manlin
Lou, Wutao
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-09
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Patients with somatoform pain disorder (SPD) suffer from somatic pain that cannot be fully explained by specific somatic pathology.
While the pain experience requires the integration of sensory and contextual processes, the cortical oscillations have been suggested to play a crucial role in pain processing and integration.
The present study is aimed at identifying the abnormalities of spontaneous cortical oscillations among patients with SPD, thus for a better understanding of the ongoing brain states in these patients.
Spontaneous electroencephalography data during a resting state with eyes open were recorded from SPD patients and healthy controls, and their cortical oscillations as well as functional connectivity were compared using both electrode-level and source-level analysis.
Compared with healthy controls, SPD patients exhibited greater resting-state alpha oscillations (8.5-12.5 Hz) at the parietal region, as reflected by both electrode-level spectral power density and exact low-resolution brain electromagnetic tomography (eLORETA) cortical current density.
A significant correlation between parietal alpha oscillation and somatization severity was observed in SPD patients, after accounting for the influence of anxiety and depression.
Functional connectivity analysis further revealed a greater frontoparietal connectivity of the resting-state alpha oscillations in SPD patients, which was indexed by the coherence between pairs of electrodes and the linear connectivity between pairs of eLORETA cortical sources.
The enhanced resting-state alpha oscillation in SPD patients could be relevant with attenuated sensory information gating and excessive integration of pain-related information, while the enhanced frontoparietal connectivity could be reflecting their sustained attention to bodily sensations and hypervigilance to somatic sensations.
American Psychological Association (APA)
Ye, Qian& Yan, Dong& Yao, Manlin& Lou, Wutao& Peng, Weiwei. 2019. Hyperexcitability of Cortical Oscillations in Patients with Somatoform Pain Disorder: A Resting-State EEG Study. Neural Plasticity،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1201075
Modern Language Association (MLA)
Ye, Qian…[et al.]. Hyperexcitability of Cortical Oscillations in Patients with Somatoform Pain Disorder: A Resting-State EEG Study. Neural Plasticity No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1201075
American Medical Association (AMA)
Ye, Qian& Yan, Dong& Yao, Manlin& Lou, Wutao& Peng, Weiwei. Hyperexcitability of Cortical Oscillations in Patients with Somatoform Pain Disorder: A Resting-State EEG Study. Neural Plasticity. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1201075
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1201075