![](/images/graphics-bg.png)
A Look into Stem Cell Therapy: Exploring the Options for Treatment of Ischemic Stroke
Joint Authors
Zhang, John H.
Reis, Cesar
Reis, Haley
Wilkinson, Michael
Akyol, Onat
Gospodarev, Vadim
Araujo, Camila
Chen, Sheng
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-22
Country of Publication
Egypt
No. of Pages
14
Abstract EN
Neural stem cells (NSCs) offer a potential therapeutic benefit in the recovery from ischemic stroke.
Understanding the role of endogenous neural stem and progenitor cells under normal physiological conditions aids in analyzing their effects after ischemic injury, including their impact on functional recovery and neurogenesis at the site of injury.
Recent animal studies have utilized unique subsets of exogenous and endogenous stem cells as well as preconditioning with pharmacologic agents to better understand the best situation for stem cell proliferation, migration, and differentiation.
These stem cell therapies provide a promising effect on stimulation of endogenous neurogenesis, neuroprotection, anti-inflammatory effects, and improved cell survival rates.
Clinical trials performed using various stem cell types show promising results to their safety and effectiveness on reducing the effects of ischemic stroke in humans.
Another important aspect of stem cell therapy discussed in this review is tracking endogenous and exogenous NSCs with magnetic resonance imaging.
This review explores the pathophysiology of NSCs on ischemic stroke, stem cell therapy studies and their effects on neurogenesis, the most recent clinical trials, and techniques to track and monitor the progress of endogenous and exogenous stem cells.
American Psychological Association (APA)
Reis, Cesar& Wilkinson, Michael& Reis, Haley& Akyol, Onat& Gospodarev, Vadim& Araujo, Camila…[et al.]. 2017. A Look into Stem Cell Therapy: Exploring the Options for Treatment of Ischemic Stroke. Stem Cells International،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1201163
Modern Language Association (MLA)
Reis, Cesar…[et al.]. A Look into Stem Cell Therapy: Exploring the Options for Treatment of Ischemic Stroke. Stem Cells International No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1201163
American Medical Association (AMA)
Reis, Cesar& Wilkinson, Michael& Reis, Haley& Akyol, Onat& Gospodarev, Vadim& Araujo, Camila…[et al.]. A Look into Stem Cell Therapy: Exploring the Options for Treatment of Ischemic Stroke. Stem Cells International. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1201163
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1201163