Induced and Evoked Properties of Vibrotactile Adaptation in the Primary Somatosensory Cortex
Joint Authors
Puts, Nicolaas A. J.
Edden, Richard A. E.
Muthukumaraswamy, Suresh
Singh, Krish D.
McGonigle, David J.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-20
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Prolonged exposure to afferent stimulation (“adaptation”) can cause profound short-term changes in the responsiveness of cortical sensory neurons.
While several models have been proposed that link adaptation to single-neuron dynamics, including GABAergic inhibition, the process is currently imperfectly understood at the whole-brain level in humans.
Here, we used magnetoencephalography (MEG) to examine the neurophysiological correlates of adaptation within SI in humans.
In one condition, a 25 Hz adapting stimulus (5 s) was followed by a 1 s 25 Hz probe (“same”), and in a second condition, the adapting stimulus was followed by a 1 s 180 Hz probe (“different”).
We hypothesized that changes in the mu-beta activity band (reflecting GABAergic processing) would be modulated differently between the “same” and “different” probe stimuli.
We show that the primary somatosensory (SI) mu-beta response to the “same” probe is significantly reduced (p=0.014) compared to the adapting stimulus, whereas the mu-beta response to the “different” probe is not (p=n.s.).
This reduction may reflect sharpening of the spatiotemporal pattern of activity after adaptation.
The stimulus onset mu-beta response did not differ between a 25 Hz adapting stimulus and a 180 Hz probe, suggesting that the mu-beta response is independent of stimulus frequency.
Furthermore, we show a sustained evoked and induced desynchronization for the duration of the adapting stimulus, consistent with invasive studies.
Our findings are important in understanding the neurophysiology underlying short-term and stimulus-induced plasticity in the human brain and shows that the brain response to tactile stimulation is altered after only brief stimulation.
American Psychological Association (APA)
Puts, Nicolaas A. J.& Edden, Richard A. E.& Muthukumaraswamy, Suresh& Singh, Krish D.& McGonigle, David J.. 2019. Induced and Evoked Properties of Vibrotactile Adaptation in the Primary Somatosensory Cortex. Neural Plasticity،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1201466
Modern Language Association (MLA)
Puts, Nicolaas A. J.…[et al.]. Induced and Evoked Properties of Vibrotactile Adaptation in the Primary Somatosensory Cortex. Neural Plasticity No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1201466
American Medical Association (AMA)
Puts, Nicolaas A. J.& Edden, Richard A. E.& Muthukumaraswamy, Suresh& Singh, Krish D.& McGonigle, David J.. Induced and Evoked Properties of Vibrotactile Adaptation in the Primary Somatosensory Cortex. Neural Plasticity. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1201466
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1201466