Phase-Amplitude Coupling of Neural Oscillations Can Be Effectively Probed with Concurrent TMS-EEG
Joint Authors
Glim, Sarah
Okazaki, Yuka O.
Nakagawa, Yumi
Mizuno, Yuji
Hanakawa, Takashi
Kitajo, Keiichi
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-31
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Despite the widespread use of transcranial magnetic stimulation (TMS), knowledge of its neurophysiological mode of action is still incomplete.
Recently, TMS has been proposed to synchronise neural oscillators and to thereby increase the detectability of corresponding oscillations at the population level.
As oscillations in the human brain are known to interact within nested hierarchies via phase-amplitude coupling, TMS might also be able to increase the macroscopic detectability of such coupling.
In a concurrent TMS-electroencephalography study, we therefore examined the technique’s influence on theta-gamma, alpha-gamma, and beta-gamma phase-amplitude coupling by delivering single-pulse TMS (sTMS) and repetitive TMS (rTMS) over the left motor cortex and right visual cortex of healthy participants.
The rTMS pulse trains were of 5 Hz, 11 Hz, and 23 Hz for the three coupling variations, respectively.
Relative to sham stimulation, all conditions showed transient but significant increases in phase-amplitude coupling at the stimulation site.
In addition, we observed enhanced coupling over various other cortical sites, with a more extensive propagation during rTMS than during sTMS.
By indicating that scalp-recorded phase-amplitude coupling can be effectively probed with TMS, these findings open the door to the technique’s application in manipulative dissections of such coupling during human cognition and behaviour in healthy and pathological conditions.
American Psychological Association (APA)
Glim, Sarah& Okazaki, Yuka O.& Nakagawa, Yumi& Mizuno, Yuji& Hanakawa, Takashi& Kitajo, Keiichi. 2019. Phase-Amplitude Coupling of Neural Oscillations Can Be Effectively Probed with Concurrent TMS-EEG. Neural Plasticity،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1201514
Modern Language Association (MLA)
Glim, Sarah…[et al.]. Phase-Amplitude Coupling of Neural Oscillations Can Be Effectively Probed with Concurrent TMS-EEG. Neural Plasticity No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1201514
American Medical Association (AMA)
Glim, Sarah& Okazaki, Yuka O.& Nakagawa, Yumi& Mizuno, Yuji& Hanakawa, Takashi& Kitajo, Keiichi. Phase-Amplitude Coupling of Neural Oscillations Can Be Effectively Probed with Concurrent TMS-EEG. Neural Plasticity. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1201514
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1201514