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Motor Control Deficits in Facial Synkinesis Patients: Neuroimaging Evidences of Cerebral Cortex Involvement
Joint Authors
Wu, JiaJia
Lu, Yechen
Hua, Xuyun
Zheng, Mouxiong
Xu, Jian-guang
Ding, Wei
Shan, Chun-lei
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-27
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
Facial synkinesis is a severe sequelae of facial nerve malfunction.
Once the synkinesis is established, it is extremely difficult for patients to recover.
Given that the restoration of motor or sensory function after peripheral nerve injury was closely related with cortical plasticity, we investigated cortical plasticity in facial synkinesis patients by the frequency-specific data which remains largely uncharacterized.
Materials and Methods.
Resting-state fMRI was conducted in 20 facial synkinesis patients and 19 healthy controls, and the amplitude of low-frequency fluctuation (ALFF) in five different frequency bands (slow-6: 0-0.01 Hz; slow-5: 0.01-0.027 Hz; slow-4: 0.027-0.073 Hz; slow-3: 0.073-0.167 Hz; and slow-2: 0.167-0.25 Hz) was calculated, respectively.
And the relationship between ALFF and clinical outcomes was also analyzed.
Results.
Comparing with the healthy controls, facial synkinesis patients showed significantly different ALFF values, mainly in the sensorimotor areas.
Furthermore, increased ALFF of the ipsilateral insula in the slow-6 band was significantly related with better facial nerve function.
Conclusion.
Increased ALFF values in the ipsilateral insula might reflect an abnormal state of hypercompensation in motor control of facial synkinesis patients.
It provided valuable spatial information about the functionally aberrant regions, which implied the possible involvement of motor control system in facial synkinesis.
American Psychological Association (APA)
Wu, JiaJia& Lu, Yechen& Zheng, Mouxiong& Hua, Xuyun& Xu, Jian-guang& Ding, Wei…[et al.]. 2019. Motor Control Deficits in Facial Synkinesis Patients: Neuroimaging Evidences of Cerebral Cortex Involvement. Neural Plasticity،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1201587
Modern Language Association (MLA)
Wu, JiaJia…[et al.]. Motor Control Deficits in Facial Synkinesis Patients: Neuroimaging Evidences of Cerebral Cortex Involvement. Neural Plasticity No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1201587
American Medical Association (AMA)
Wu, JiaJia& Lu, Yechen& Zheng, Mouxiong& Hua, Xuyun& Xu, Jian-guang& Ding, Wei…[et al.]. Motor Control Deficits in Facial Synkinesis Patients: Neuroimaging Evidences of Cerebral Cortex Involvement. Neural Plasticity. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1201587
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1201587