Structure and Functions of Blood Vessels and Vascular Niches in Bone
Author
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-17
Country of Publication
Egypt
No. of Pages
10
Abstract EN
Bone provides nurturing microenvironments for an array of cell types that coordinate important physiological functions of the skeleton, such as energy metabolism, mineral homeostasis, osteogenesis, and haematopoiesis.
Endothelial cells form an intricate network of blood vessels that organises and sustains various microenvironments in bone.
The recent identification of heterogeneity in the bone vasculature supports the existence of multiple vascular niches within the bone marrow compartment.
A unique combination of cells and factors defining a particular microenvironment, supply regulatory signals to mediate a specific function.
This review discusses recent developments in our understanding of vascular niches in bone that play a critical role in regulating the behaviour of multipotent haematopoietic and mesenchymal stem cells during development and homeostasis.
American Psychological Association (APA)
Ramasamy, Saravana K.. 2017. Structure and Functions of Blood Vessels and Vascular Niches in Bone. Stem Cells International،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1201708
Modern Language Association (MLA)
Ramasamy, Saravana K.. Structure and Functions of Blood Vessels and Vascular Niches in Bone. Stem Cells International No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1201708
American Medical Association (AMA)
Ramasamy, Saravana K.. Structure and Functions of Blood Vessels and Vascular Niches in Bone. Stem Cells International. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1201708
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1201708