Human Long Noncoding RNA Regulation of Stem Cell Potency and Differentiation
Joint Authors
Hwang, Ki-Chul
Lee, Seahyoung
Seo, Hyang-Hee
Lee, Chang Youn
Lee, Jiyun
Shin, Sunhye
Kim, Sang Woo
Lim, Soyeon
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-30
Country of Publication
Egypt
No. of Pages
10
Abstract EN
Because of their capability of differentiation into lineage-specific cells, stem cells are an attractive therapeutic modality in regenerative medicine.
To develop an effective stem cell-based therapeutic strategy with predictable results, deeper understanding of the underlying molecular mechanisms of stem cell differentiation and/or pluripotency maintenance is required.
Thus, reviewing the key factors involved in the transcriptional and epigenetic regulation of stem cell differentiation and maintenance is important.
Accumulating data indicate that long noncoding RNAs (lncRNAs) mediate numerous biological processes, including stem cell differentiation and maintenance.
Here, we review recent findings on the human lncRNA regulation of stem cell potency and differentiation.
Although the clinical implication of these lncRNAs is only beginning to be elucidated, it is anticipated that lncRNAs will become important therapeutic targets in the near future.
American Psychological Association (APA)
Lee, Seahyoung& Seo, Hyang-Hee& Lee, Chang Youn& Lee, Jiyun& Shin, Sunhye& Kim, Sang Woo…[et al.]. 2017. Human Long Noncoding RNA Regulation of Stem Cell Potency and Differentiation. Stem Cells International،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1201966
Modern Language Association (MLA)
Lee, Seahyoung…[et al.]. Human Long Noncoding RNA Regulation of Stem Cell Potency and Differentiation. Stem Cells International No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1201966
American Medical Association (AMA)
Lee, Seahyoung& Seo, Hyang-Hee& Lee, Chang Youn& Lee, Jiyun& Shin, Sunhye& Kim, Sang Woo…[et al.]. Human Long Noncoding RNA Regulation of Stem Cell Potency and Differentiation. Stem Cells International. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1201966
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1201966