Effects of Neuropeptide Y on Stem Cells and Their Potential Applications in Disease Therapy
Joint Authors
Peng, Song
Zhou, You-li
Song, Zhi-yuan
Lin, Shu
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-03
Country of Publication
Egypt
No. of Pages
12
Abstract EN
Neuropeptide Y (NPY), a 36-amino acid peptide, is widely distributed in the central and peripheral nervous systems and other peripheral tissues.
It takes part in regulating various biological processes including food intake, circadian rhythm, energy metabolism, and neuroendocrine secretion.
Increasing evidence indicates that NPY exerts multiple regulatory effects on stem cells.
As a kind of primitive and undifferentiated cells, stem cells have the therapeutic potential to replace damaged cells, secret paracrine molecules, promote angiogenesis, and modulate immunity.
Stem cell-based therapy has been demonstrated effective and considered as one of the most promising treatments for specific diseases.
However, several limitations still hamper its application, such as poor survival and low differentiation and integration rates of transplanted stem cells.
The regulatory effects of NPY on stem cell survival, proliferation, and differentiation may be helpful to overcome these limitations and facilitate the application of stem cell-based therapy.
In this review, we summarized the regulatory effects of NPY on stem cells and discussed their potential applications in disease therapy.
American Psychological Association (APA)
Peng, Song& Zhou, You-li& Song, Zhi-yuan& Lin, Shu. 2017. Effects of Neuropeptide Y on Stem Cells and Their Potential Applications in Disease Therapy. Stem Cells International،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1201983
Modern Language Association (MLA)
Peng, Song…[et al.]. Effects of Neuropeptide Y on Stem Cells and Their Potential Applications in Disease Therapy. Stem Cells International No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1201983
American Medical Association (AMA)
Peng, Song& Zhou, You-li& Song, Zhi-yuan& Lin, Shu. Effects of Neuropeptide Y on Stem Cells and Their Potential Applications in Disease Therapy. Stem Cells International. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1201983
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1201983