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Basosquamous Carcinoma: A Single Centre Clinicopathological Evaluation and Proposal of an Evidence-Based Protocol
Joint Authors
Oldbury, Jordan W.
Wain, Richard A. J.
Abas, Sameera
Dobson, Christopher M.
Iyer, Srinivasan S.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Basosquamous carcinoma (BSC) is an uncommon skin malignancy with significant invasive and metastatic potential.
There are currently no clear management guidelines.
This study evaluates the management and outcomes of patients diagnosed with BSC over a 7-year period.
We present an evidence-based unit protocol for the management of BSC.
All patients treated for BSC between 2009 and 2015 were reviewed.
Data collected included patient demographics, tumour-specific information, management strategy, presence of recurrence or metastasis, and details of follow-up.
74 patients were identified, making this one of the largest cohorts of BSC patients reported.
Mean age at diagnosis was 75.4 years, with a male:female ratio of 1.6:1.
The most common tumour site was the head and neck (n=43, 58.1%).
All tumours were graded at pT1 (n=51) or pT2 (n=23).
Inadequate excision occurred in 17 patients (23%).
Mean excision margins were >4mm peripherally and deep.
Inadequately excised BSCs were further treated with wide local excision (n=6) or radiotherapy (n=5), or both (n=1).
There were no cases of local recurrence or metastatic disease.
This study demonstrates a cohort of patients with BSCs that appear less aggressive than previously reported.
Current management with surgical excision appears to produce adequate results.
However, an evidence-based guideline is still lacking.
American Psychological Association (APA)
Oldbury, Jordan W.& Wain, Richard A. J.& Abas, Sameera& Dobson, Christopher M.& Iyer, Srinivasan S.. 2018. Basosquamous Carcinoma: A Single Centre Clinicopathological Evaluation and Proposal of an Evidence-Based Protocol. Journal of Skin Cancer،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1202350
Modern Language Association (MLA)
Oldbury, Jordan W.…[et al.]. Basosquamous Carcinoma: A Single Centre Clinicopathological Evaluation and Proposal of an Evidence-Based Protocol. Journal of Skin Cancer No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1202350
American Medical Association (AMA)
Oldbury, Jordan W.& Wain, Richard A. J.& Abas, Sameera& Dobson, Christopher M.& Iyer, Srinivasan S.. Basosquamous Carcinoma: A Single Centre Clinicopathological Evaluation and Proposal of an Evidence-Based Protocol. Journal of Skin Cancer. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1202350
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1202350