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Gd3+-Doped Magnetic Nanoparticles for Biomedical Applications
Joint Authors
Soldatov, A. V.
Bugaev, Aram L.
Budnyk, A. P.
Lastovina, T. A.
Polyakov, V. A.
Vetlitsyna-Novikova, K. S.
Sirota, M. A.
Abdulvakhidov, K. G.
Fedorenko, A. G.
Podlesnaya, E. O.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-02
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Magnetic nanoparticles (MNPs) made of iron oxides with cubic symmetry (Fe3O4, γ-Fe2O3) are demanded objects for multipurpose in biomedical applications as contrast agents for magnetic resonance imaging, magnetically driven carriers for drug delivery, and heaters in hyperthermia cancer treatment.
An optimum balance between the right particle size and good magnetic response can be reached by a selection of a synthesis method and by doping with rare earth elements.
Here, we present a microwave-assisted polyol synthesis of iron oxide MNPs with actual gadolinium (III) doping from 0.5 to 5.1 mol.%.
The resulting MNPs have an average size of 14 nm with narrow size distribution.
Their surface was covered by a glycol layer, which prevents aggregation and improves biocompatibility.
The magnetic hyperthermia test was performed on 1 and 2 mg/ml aqueous colloidal solutions of MNPs and demonstrated their ability to rise the temperature by 3°C during a 20–30 min run.
Therefore, the obtained Gd3+ MNPs are the promising material for biomedicine.
American Psychological Association (APA)
Budnyk, A. P.& Lastovina, T. A.& Bugaev, Aram L.& Polyakov, V. A.& Vetlitsyna-Novikova, K. S.& Sirota, M. A.…[et al.]. 2018. Gd3+-Doped Magnetic Nanoparticles for Biomedical Applications. Journal of Spectroscopy،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1202415
Modern Language Association (MLA)
Budnyk, A. P.…[et al.]. Gd3+-Doped Magnetic Nanoparticles for Biomedical Applications. Journal of Spectroscopy No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1202415
American Medical Association (AMA)
Budnyk, A. P.& Lastovina, T. A.& Bugaev, Aram L.& Polyakov, V. A.& Vetlitsyna-Novikova, K. S.& Sirota, M. A.…[et al.]. Gd3+-Doped Magnetic Nanoparticles for Biomedical Applications. Journal of Spectroscopy. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1202415
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1202415