![](/images/graphics-bg.png)
Different Spectrophotometric Methods Manipulating Ratio Spectra Applied for the Analysis of Aclidinium in Duaklir® Genuair® Inhalation Powder
Joint Authors
Attia, Khalid A. M.
El-Abasawi, Nasr M.
El-Olemy, Ahmed
Serag, Ahmed
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Two simple, accurate, and selective spectrophotometric methods were developed to determine aclidinium in the presence of formoterol as interferent compound in Duaklir Genuair inhalation powder.
The methods under study are ratio derivative and ratio subtraction spectrophotometric methods.
These methods are based on different mathematical processing of the obtained ratio spectra.
The methods are linear over the concentration range of 5–50 µg/mL for aclidinium and validated according to the ICH guidelines.
The accuracy and precision are found to be within the acceptable limits and assessed by applying the standard addition technique.
The specificity of the proposed methods was tested using laboratory-prepared mixtures.
Furthermore, the methods were statistically compared to the reported RP-HPLC method, and good results were obtained.
American Psychological Association (APA)
Attia, Khalid A. M.& El-Abasawi, Nasr M.& El-Olemy, Ahmed& Serag, Ahmed. 2018. Different Spectrophotometric Methods Manipulating Ratio Spectra Applied for the Analysis of Aclidinium in Duaklir® Genuair® Inhalation Powder. Journal of Spectroscopy،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1202561
Modern Language Association (MLA)
Attia, Khalid A. M.…[et al.]. Different Spectrophotometric Methods Manipulating Ratio Spectra Applied for the Analysis of Aclidinium in Duaklir® Genuair® Inhalation Powder. Journal of Spectroscopy No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1202561
American Medical Association (AMA)
Attia, Khalid A. M.& El-Abasawi, Nasr M.& El-Olemy, Ahmed& Serag, Ahmed. Different Spectrophotometric Methods Manipulating Ratio Spectra Applied for the Analysis of Aclidinium in Duaklir® Genuair® Inhalation Powder. Journal of Spectroscopy. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1202561
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1202561