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Chitosan-Capped Au Nanoparticles for Laser Photothermal Ablation Therapy: UV-Vis Characterization and Optothermal Performances
Joint Authors
Margheri, Giancarlo
Trigari, Silvana
Berti, Mariabeatrice
Muniz Miranda, Maurizio
Traversi, R.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-10
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
We have reported on the synthesis and characterization of near-infrared- (NIR-) absorbing colloidal nanoparticles prepared by exploiting the one-step reaction of HAuCl4 and Na2S2O3, followed by their stabilization with chitosan.
This reaction also produces a big amount of unwanted nanoparticles detuned with respect to the NIR spectral region.
For this reason, it is usually assumed that the product has to be filtered and enriched to enhance its NIR absorption, and the possible exploitation of the simpler raw product has never been worthy to be considered.
Aiming to investigate this missing aspect, we chose to avoid the purification steps and rather focused on the preparation of the unrefined colloid, identifying the synthesis conditions that maximize its NIR absorbance and, subsequently, testing it as an optothermal transducer by measuring its molar heating rate (MHR).
As expected, we found that the performances of the raw colloid are indeed lower than those of its refined version, but only to a limited extent.
Moreover, MHR is unexpectedly higher than that deducible for other classical NIR-absorbing nanoparticles, like Au nanorods or Au nanostars.
Thus, the product of the simpler preparation protocol appears as a competitive trade-off solution between easy manufacturing and optothermal performances.
American Psychological Association (APA)
Margheri, Giancarlo& Trigari, Silvana& Berti, Mariabeatrice& Muniz Miranda, Maurizio& Traversi, R.. 2018. Chitosan-Capped Au Nanoparticles for Laser Photothermal Ablation Therapy: UV-Vis Characterization and Optothermal Performances. Journal of Spectroscopy،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1202620
Modern Language Association (MLA)
Margheri, Giancarlo…[et al.]. Chitosan-Capped Au Nanoparticles for Laser Photothermal Ablation Therapy: UV-Vis Characterization and Optothermal Performances. Journal of Spectroscopy No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1202620
American Medical Association (AMA)
Margheri, Giancarlo& Trigari, Silvana& Berti, Mariabeatrice& Muniz Miranda, Maurizio& Traversi, R.. Chitosan-Capped Au Nanoparticles for Laser Photothermal Ablation Therapy: UV-Vis Characterization and Optothermal Performances. Journal of Spectroscopy. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1202620
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1202620