Cerebral Blood Flow Alterations in High Myopia: An Arterial Spin Labeling Study
Joint Authors
Wang, Zhenchang
Wang, Huihui
Li, Shanshan
Chen, Xi
Wang, Yanling
Li, Jing
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
The aim of this study was to explore cerebral blood flow (CBF) alterations in subjects with high myopia (HM) using three-dimensional pseudocontinuous arterial spin labeling (3D-pcASL).
Methods.
A total of sixteen patients with bilateral HM and sixteen age- and sex-matched healthy controls (HCs) were recruited.
All subjects were right-handed.
Image data preprocessing was performed using SPM8 and the DPABI toolbox.
Clinical parameters were acquired in the HM group.
Two-sample t-tests and Pearson correlation analysis were applied in this study.
Results.
Compared to HCs, patients with HM exhibited significantly increased CBF in the bilateral cerebellum, and no decreases in CBF were detected in the brain.
However, no relationship was found between the mean CBF values in the different brain areas and the disease duration (P>0.05).
Conclusions.
Using ASL analysis, we detected aberrant blood perfusion in the cerebellum in HM patients, contributing to a better understanding of brain abnormalities and brain plasticity through a different perspective.
American Psychological Association (APA)
Wang, Huihui& Li, Shanshan& Chen, Xi& Wang, Yanling& Li, Jing& Wang, Zhenchang. 2020. Cerebral Blood Flow Alterations in High Myopia: An Arterial Spin Labeling Study. Neural Plasticity،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1202715
Modern Language Association (MLA)
Wang, Huihui…[et al.]. Cerebral Blood Flow Alterations in High Myopia: An Arterial Spin Labeling Study. Neural Plasticity No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1202715
American Medical Association (AMA)
Wang, Huihui& Li, Shanshan& Chen, Xi& Wang, Yanling& Li, Jing& Wang, Zhenchang. Cerebral Blood Flow Alterations in High Myopia: An Arterial Spin Labeling Study. Neural Plasticity. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1202715
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1202715