Neuropharmacological Effects of Mesaconitine: Evidence from Molecular and Cellular Basis of Neural Circuit
Joint Authors
Zhao, Lihong
Sun, Zhihui
Yang, Limin
Cui, Ranji
Yang, Wei
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-21
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Mesaconitine (MA), a diester-diterpenoid alkaloid in aconite roots, is considered to be one of the most important bioactive ingredients.
In this review, we summarized its neuropharmacological effects, including analgesic effects and antiepileptiform effects.
Mesaconitine can act on the central noradrenergic system and the serotonin system; behaving like the norepinephrine reuptake inhibitors and tricyclic antidepressants that increase norepinephrine levels in stress-induced depression.
Therefore, the possible perspectives for future studies on the depression of MA were also discussed as well.
The pharmacological effect of MA on depression is worthy of further study.
American Psychological Association (APA)
Sun, Zhihui& Yang, Limin& Zhao, Lihong& Cui, Ranji& Yang, Wei. 2020. Neuropharmacological Effects of Mesaconitine: Evidence from Molecular and Cellular Basis of Neural Circuit. Neural Plasticity،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1202793
Modern Language Association (MLA)
Sun, Zhihui…[et al.]. Neuropharmacological Effects of Mesaconitine: Evidence from Molecular and Cellular Basis of Neural Circuit. Neural Plasticity No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1202793
American Medical Association (AMA)
Sun, Zhihui& Yang, Limin& Zhao, Lihong& Cui, Ranji& Yang, Wei. Neuropharmacological Effects of Mesaconitine: Evidence from Molecular and Cellular Basis of Neural Circuit. Neural Plasticity. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1202793
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1202793