Stem Cell-Based Therapeutic Approaches to Restore Sensorineural Hearing Loss in Mammals
Joint Authors
He, Shuangba
Waqas, Muhammad
Us-Salam, Iram
Bibi, Zainab
Wang, Yunfeng
Li, He
Zhu, Zhongshou
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-01
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The hair cells that reside in the cochlear sensory epithelium are the fundamental sensory structures responsible for understanding the mechanical sound waves evoked in the environment.
The intense damage to these sensory structures may result in permanent hearing loss.
The present strategies to rehabilitate the hearing function include either hearing aids or cochlear implants that may recover the hearing capability of deaf patients to a limited extent.
Therefore, much attention has been paid on developing regenerative therapies to regenerate/replace the lost hair cells to treat the damaged cochlear sensory epithelium.
The stem cell therapy is a promising approach to develop the functional hair cells and neuronal cells from endogenous and exogenous stem cell pool to recover hearing loss.
In this review, we specifically discuss the potential of different kinds of stem cells that hold the potential to restore sensorineural hearing loss in mammals and comprehensively explain the current therapeutic applications of stem cells in both the human and mouse inner ear to regenerate/replace the lost hair cells and spiral ganglion neurons.
American Psychological Association (APA)
Waqas, Muhammad& Us-Salam, Iram& Bibi, Zainab& Wang, Yunfeng& Li, He& Zhu, Zhongshou…[et al.]. 2020. Stem Cell-Based Therapeutic Approaches to Restore Sensorineural Hearing Loss in Mammals. Neural Plasticity،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1202853
Modern Language Association (MLA)
Waqas, Muhammad…[et al.]. Stem Cell-Based Therapeutic Approaches to Restore Sensorineural Hearing Loss in Mammals. Neural Plasticity No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1202853
American Medical Association (AMA)
Waqas, Muhammad& Us-Salam, Iram& Bibi, Zainab& Wang, Yunfeng& Li, He& Zhu, Zhongshou…[et al.]. Stem Cell-Based Therapeutic Approaches to Restore Sensorineural Hearing Loss in Mammals. Neural Plasticity. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1202853
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1202853