Acupuncture Modulates Disrupted Whole-Brain Network after Ischemic Stroke: Evidence Based on Graph Theory Analysis
Joint Authors
Cui, Fangyuan
Jin, He
Zhang, Yong
Li, Kuangshi
Zou, Yihuai
Liu, Hongwei
Han, Xiao
Bai, Lijun
Ning, Yanzhe
Ren, Yi
Chen, Pei
Jiang, Lan
Zhang, Hua
Tan, Zhongjian
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
Stroke can lead to disruption of the whole-brain network in patients.
Acupuncture can modulate the functional network on a large-scale level in healthy individuals.
However, whether and how acupuncture can make a potential impact on the disrupted whole-brain network after ischemic stroke remains elusive.
Methods.
26 stroke patients with a right hemispheric subcortical infarct were recruited.
We gathered the functional magnetic resonance imaging (fMRI) from patients with stroke and healthy controls in the resting state and after acupuncture intervention, to investigate the instant alterations of the large-scale functional networks.
The graph theory analysis was applied using the GRETNA and SPM12 software to construct the whole-brain network and yield the small-world parameters and network efficiency.
Results.
Compared with the healthy subjects, the stroke patients had a decreased normalized small-worldness (σ), global efficiency (Eg), and the mean local efficiency (Eloc) of the whole-brain network in the resting state.
There was a correlation between the duration after stroke onset and Eloc.
Acupuncture improved the patients’ clustering coefficient (Cp) and Eloc but did not make a significant impact on the σ and Eg.
The postacupuncture variables of the whole-brain network had no association with the time of onset.
Conclusion.
The poststroke whole-brain network tended to a random network with reduced network efficiency.
Acupuncture was able to modulate the disrupted patterns of the whole-brain network following the subcortical ischemic stroke.
Our findings shed light on the potential mechanisms of the functional reorganization on poststroke brain networks involving acupuncture intervention from a large-scale perspective.
American Psychological Association (APA)
Han, Xiao& Jin, He& Li, Kuangshi& Ning, Yanzhe& Jiang, Lan& Chen, Pei…[et al.]. 2020. Acupuncture Modulates Disrupted Whole-Brain Network after Ischemic Stroke: Evidence Based on Graph Theory Analysis. Neural Plasticity،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1202889
Modern Language Association (MLA)
Han, Xiao…[et al.]. Acupuncture Modulates Disrupted Whole-Brain Network after Ischemic Stroke: Evidence Based on Graph Theory Analysis. Neural Plasticity No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1202889
American Medical Association (AMA)
Han, Xiao& Jin, He& Li, Kuangshi& Ning, Yanzhe& Jiang, Lan& Chen, Pei…[et al.]. Acupuncture Modulates Disrupted Whole-Brain Network after Ischemic Stroke: Evidence Based on Graph Theory Analysis. Neural Plasticity. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1202889
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1202889