Diagnostic Accuracy of Preoperative Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Detecting Occult Papillary Thyroid Microcarcinomas in Benign Multinodular Goitres
Joint Authors
Korkolis, Dimitris P.
Balalis, Dimitrios
Plataniotis, Georgios
Gontikakis, Emmanouil
Tseleni-Balafouta, Sophia
Tzelves, Lazaros
Tzortzopoulou, Adelais
Manatakis, Dimitrios K.
Sakorafas, George H.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To investigate the diagnostic accuracy of neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte (PLR) ratios in detecting occult papillary thyroid microcarcinomas in benign, multinodular goitres.
Methods.
397 total thyroidectomy patients were identified from the institutional thyroid surgery database between 2007 and 2016 (94 males, 303 females, mean age 53 ± 14.5 years).
NLR and PLR were calculated as the absolute neutrophil and absolute platelet counts divided by the absolute lymphocyte count, respectively, based on the preoperative complete blood cell count.
Results.
NLR was significantly higher in carcinomas and microcarcinomas compared to benign pathology (p=0.026), whereas a direct association could not be established for PLR.
Both NLR and PLR scored low in all parameters of diagnostic accuracy, with overall accuracy ranging between 45 and 50%.
Conclusions.
As surrogate indices of the systemic inflammatory response, NLR and PLR are inexpensive and universally available from routine blood tests.
Although we found higher NLR values in cases of malignancy, NLR and PLR cannot effectively predict the presence of occult papillary microcarcinomas in otherwise benign, multinodular goitres.
American Psychological Association (APA)
Manatakis, Dimitrios K.& Tseleni-Balafouta, Sophia& Tzelves, Lazaros& Balalis, Dimitrios& Tzortzopoulou, Adelais& Korkolis, Dimitris P.…[et al.]. 2018. Diagnostic Accuracy of Preoperative Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Detecting Occult Papillary Thyroid Microcarcinomas in Benign Multinodular Goitres. Journal of Thyroid Research،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1203066
Modern Language Association (MLA)
Manatakis, Dimitrios K.…[et al.]. Diagnostic Accuracy of Preoperative Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Detecting Occult Papillary Thyroid Microcarcinomas in Benign Multinodular Goitres. Journal of Thyroid Research No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1203066
American Medical Association (AMA)
Manatakis, Dimitrios K.& Tseleni-Balafouta, Sophia& Tzelves, Lazaros& Balalis, Dimitrios& Tzortzopoulou, Adelais& Korkolis, Dimitris P.…[et al.]. Diagnostic Accuracy of Preoperative Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Detecting Occult Papillary Thyroid Microcarcinomas in Benign Multinodular Goitres. Journal of Thyroid Research. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1203066
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1203066