Autophagy-Associated lncRNAs: Promising Targets for Neurological Disease Diagnosis and Therapy
Joint Authors
Xu, Xiangming
Cui, Lili
Zhong, Wangtao
Cai, Yujie
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-22
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Neurological diseases are a major threat to global public health and prosperity.
The number of patients with neurological diseases is increasing due to the population aging and increasing life expectancy.
Autophagy is one of the crucial mechanisms to maintain nerve cellular homeostasis.
Numerous studies have demonstrated that autophagy plays a dual role in neurological diseases.
Long noncoding RNAs (lncRNAs) are a vital class of noncoding RNAs with a length of more than 200 nucleotides and cannot encode proteins themselves but are expressed in most neurological diseases.
An early phase, emerging knowledge has revealed that long noncoding RNAs (lncRNAs) are crucial in autophagy regulation.
Furthermore, autophagy-associated lncRNAs can promote the development of neurological diseases or slow their progression.
In this review, we introduce a general overview of lncRNA functional mechanisms and summarizes the recent progress of lncRNAs on autophagy regulation in neurological diseases to reveal possible novel therapeutic targets or useful biomarkers.
American Psychological Association (APA)
Xu, Xiangming& Cui, Lili& Zhong, Wangtao& Cai, Yujie. 2020. Autophagy-Associated lncRNAs: Promising Targets for Neurological Disease Diagnosis and Therapy. Neural Plasticity،Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1203085
Modern Language Association (MLA)
Xu, Xiangming…[et al.]. Autophagy-Associated lncRNAs: Promising Targets for Neurological Disease Diagnosis and Therapy. Neural Plasticity No. 2020 (2020), pp.1-13.
https://search.emarefa.net/detail/BIM-1203085
American Medical Association (AMA)
Xu, Xiangming& Cui, Lili& Zhong, Wangtao& Cai, Yujie. Autophagy-Associated lncRNAs: Promising Targets for Neurological Disease Diagnosis and Therapy. Neural Plasticity. 2020. Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1203085
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1203085