Transcranial Direct Current Stimulation Enhances Episodic Memory in Healthy Older Adults by Modulating Retrieval-Specific Activation
Joint Authors
Huang, Jia
Huo, Lijuan
Zheng, Zhiwei
Li, Jin
Li, Juan
Li, Rui
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-07
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Memory decline has become an issue of major importance in the aging society.
Anodal transcranial direct current stimulation (atDCS) is a viable tool to counteract age-associated episodic memory deterioration.
However, the underlying neural mechanisms are unclear.
In this single-blind, sham-controlled study, we combined atDCS and functional magnetic resonance imaging to assess the behavioral and neural consequences of multiple-session atDCS in older adults.
Forty-nine healthy older adults received either 10 sessions of anodal or sham stimulation over the left dorsolateral prefrontal cortex.
Before and after stimulation, participants performed a source memory task in the MRI scanner.
Compared to sham stimulation, atDCS significantly improved item memory performance.
Additionally, atDCS significantly increased regional brain activity around the stimulation area in the prefrontal cortex and extended to the bilateral anterior cingulate cortex.
Neural changes in the prefrontal cortex correlated with memory gains.
Our findings therefore indicate that multiple-session offline atDCS may improve memory in older adults by inducing neural alterations.
American Psychological Association (APA)
Huo, Lijuan& Zheng, Zhiwei& Huang, Jia& Li, Rui& Li, Jin& Li, Juan. 2020. Transcranial Direct Current Stimulation Enhances Episodic Memory in Healthy Older Adults by Modulating Retrieval-Specific Activation. Neural Plasticity،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1203096
Modern Language Association (MLA)
Huo, Lijuan…[et al.]. Transcranial Direct Current Stimulation Enhances Episodic Memory in Healthy Older Adults by Modulating Retrieval-Specific Activation. Neural Plasticity No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1203096
American Medical Association (AMA)
Huo, Lijuan& Zheng, Zhiwei& Huang, Jia& Li, Rui& Li, Jin& Li, Juan. Transcranial Direct Current Stimulation Enhances Episodic Memory in Healthy Older Adults by Modulating Retrieval-Specific Activation. Neural Plasticity. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1203096
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1203096