Management Strategies for Posttransplant Diabetes Mellitus after Heart Transplantation: A Review
Joint Authors
Cehic, Matthew G.
Nundall, Nishant
Greenfield, Jerry R.
Macdonald, Peter S.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-29
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Posttransplant diabetes mellitus (PTDM) is a well-recognized complication of heart transplantation and is associated with increased morbidity and mortality.
Previous studies have yielded wide ranging estimates in the incidence of PTDM due in part to variable definitions applied.
In addition, there is a limited published data on the management of PTDM after heart transplantation and a paucity of studies examining the effects of newer classes of hypoglycaemic drug therapies.
In this review, we discuss the role of established glucose-lowering therapies and the rationale and emerging clinical evidence that supports the role of incretin-based therapies (glucagon like peptide- (GLP-) 1 agonists and dipeptidyl peptidase- (DPP-) 4 inhibitors) and sodium-glucose cotransporter 2 (SGLT2) inhibitors in the management of PTDM after heart transplantation.
Recently published Consensus Guidelines for the diagnosis of PTDM will hopefully lead to more consistent approaches to the diagnosis of PTDM and provide a platform for the larger-scale multicentre trials that will be needed to determine the role of these newer therapies in the management of PTDM.
American Psychological Association (APA)
Cehic, Matthew G.& Nundall, Nishant& Greenfield, Jerry R.& Macdonald, Peter S.. 2018. Management Strategies for Posttransplant Diabetes Mellitus after Heart Transplantation: A Review. Journal of Transplantation،Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1203119
Modern Language Association (MLA)
Cehic, Matthew G.…[et al.]. Management Strategies for Posttransplant Diabetes Mellitus after Heart Transplantation: A Review. Journal of Transplantation No. 2018 (2018), pp.1-14.
https://search.emarefa.net/detail/BIM-1203119
American Medical Association (AMA)
Cehic, Matthew G.& Nundall, Nishant& Greenfield, Jerry R.& Macdonald, Peter S.. Management Strategies for Posttransplant Diabetes Mellitus after Heart Transplantation: A Review. Journal of Transplantation. 2018. Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1203119
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1203119