Modulation of Astrocytes on Mode Selection of Neuron Firing Driven by Electromagnetic Induction
Joint Authors
Wang, Zuo
Yuan, Zhixuan
Gao, Zhongquan
Feng, Peihua
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-01
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Both of astrocytes and electromagnetic induction are magnificent to modulate neuron firing by introducing feedback currents to membrane potential.
An improved astro-neuron model considering both of the two factors is employed to investigate their different roles in modulation.
The mixing mode, defined by combination of period bursting and depolarization blockage, characterizes the effect of astrocytes.
Mixing mode and period bursting alternatively appear in parameter space with respect to the amplitude of feedback current on neuron from astrocyte modulation.
However, magnetic flux obviously plays a role of neuron firing inhibition.
It not only repels the mixing mode but also suppresses period bursting.
The mixing mode becomes period bursting mode and even resting state when astrocytes are hyperexcitable.
Abnormal activities of astrocytes are capable to induce depolarization blockage to compose the mixing mode together with bursting mode.
But electromagnetic induction shows its strong ability of inhibition of neuron firing, which is also illustrated in the bifurcation diagram.
Indeed, the combination of the two factors and appropriate choice of parameters show the great potential to control disorder of neuron firing like epilepsy.
American Psychological Association (APA)
Gao, Zhongquan& Yuan, Zhixuan& Wang, Zuo& Feng, Peihua. 2020. Modulation of Astrocytes on Mode Selection of Neuron Firing Driven by Electromagnetic Induction. Neural Plasticity،Vol. 2020, no. 2020, pp.1-18.
https://search.emarefa.net/detail/BIM-1203161
Modern Language Association (MLA)
Gao, Zhongquan…[et al.]. Modulation of Astrocytes on Mode Selection of Neuron Firing Driven by Electromagnetic Induction. Neural Plasticity No. 2020 (2020), pp.1-18.
https://search.emarefa.net/detail/BIM-1203161
American Medical Association (AMA)
Gao, Zhongquan& Yuan, Zhixuan& Wang, Zuo& Feng, Peihua. Modulation of Astrocytes on Mode Selection of Neuron Firing Driven by Electromagnetic Induction. Neural Plasticity. 2020. Vol. 2020, no. 2020, pp.1-18.
https://search.emarefa.net/detail/BIM-1203161
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1203161