Current Progress of Research on Neurodegenerative Diseases of Salvianolic Acid B
Joint Authors
Zhang, Qian
Yang, Hao
Zhao, Rui
Liu, Xifang
Zhang, Lixin
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Salvia miltiorrhiza Bunge (Lamiaceae), one of the most commonly used traditional Chinese herbs, is widely used for the treatment of cardiovascular disease, cerebrovascular disease, Alzheimer’s disease, and Parkinson’s disease in clinical practice.
Salvianolic acid B (Sal B, C36H30O16, FW=718.62) is the main water-soluble active ingredient of Salvia miltiorrhiza Bunge, which performs prophylactic and therapeutic activities against neurodegenerative diseases.
So far, numerous studies have proved that multiple factors and mechanisms are involved in the pathological process of neurodegenerative diseases, including amyloid β (Aβ) aggregation and fibril formation, hyperphosphorylation of tau protein, neuroinflammation, oxidative-stress damage, mitochondrial dysfunction, and neuron apoptosis.
This study is aimed at reviewing experimental studies and describing the possible mechanisms of Sal B on neurodegenerative diseases.
American Psychological Association (APA)
Zhao, Rui& Liu, Xifang& Zhang, Lixin& Yang, Hao& Zhang, Qian. 2019. Current Progress of Research on Neurodegenerative Diseases of Salvianolic Acid B. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1203187
Modern Language Association (MLA)
Zhao, Rui…[et al.]. Current Progress of Research on Neurodegenerative Diseases of Salvianolic Acid B. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1203187
American Medical Association (AMA)
Zhao, Rui& Liu, Xifang& Zhang, Lixin& Yang, Hao& Zhang, Qian. Current Progress of Research on Neurodegenerative Diseases of Salvianolic Acid B. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1203187
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1203187