Altered Brain Activity and Functional Connectivity in Unilateral Sudden Sensorineural Hearing Loss
Joint Authors
Qin, Peng
Liu, Chengcheng
Chen, Jiawei
Gao, Wei
Lu, Lianjun
Zi, Dingjing
Ding, Xuerui
Cui, Guangbin
Hu, Bo
Yu, Ying
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-22
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background.
Sudden sensorineural hearing loss (SSNHL) is an otologic emergency and could lead to social difficulties and mental disorders in some patients.
Although many studies have analyzed altered brain function in populations with hearing loss, little information is available about patients with idiopathic SSNHL.
This study is aimed at investigating brain functional changes in SSNHL via functional magnetic resonance imaging (fMRI).
Methods.
Thirty-six patients with SSNHL and thirty well-matched normal hearing individuals underwent resting-state fMRI.
Amplitude of low-frequency fluctuation (ALFF), fractional ALFF (fALFF), and functional connectivity (FC) values were calculated.
Results.
In the SSNHL patients, ALFF and fALFF were significantly increased in the bilateral putamen but decreased in the right calcarine cortex, right middle temporal gyrus (MTG), and right precentral gyrus.
Widespread increases in FC were observed between brain regions, mainly including the bilateral auditory cortex, bilateral visual cortex, left striatum, left angular gyrus (AG), bilateral precuneus, and bilateral limbic lobes in patients with SSNHL.
No decreased FC was observed.
Conclusion.
SSNHL causes functional alterations in brain regions, mainly in the striatum, auditory cortex, visual cortex, MTG, AG, precuneus, and limbic lobes within the acute period of hearing loss.
American Psychological Association (APA)
Chen, Jiawei& Hu, Bo& Qin, Peng& Gao, Wei& Liu, Chengcheng& Zi, Dingjing…[et al.]. 2020. Altered Brain Activity and Functional Connectivity in Unilateral Sudden Sensorineural Hearing Loss. Neural Plasticity،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1203193
Modern Language Association (MLA)
Chen, Jiawei…[et al.]. Altered Brain Activity and Functional Connectivity in Unilateral Sudden Sensorineural Hearing Loss. Neural Plasticity No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1203193
American Medical Association (AMA)
Chen, Jiawei& Hu, Bo& Qin, Peng& Gao, Wei& Liu, Chengcheng& Zi, Dingjing…[et al.]. Altered Brain Activity and Functional Connectivity in Unilateral Sudden Sensorineural Hearing Loss. Neural Plasticity. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1203193
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1203193