Effects of Glycerol and Sodium Pentaborate Formulation on Prevention of Postoperative Peritoneal Adhesion Formation
Joint Authors
Sahin, Fikrettin
Catal, Ruzgar
Javadov, Mirkhaliq
Cumbul, Alev
Aysan, Erhan
Source
Obstetrics and Gynecology International
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-06
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Postoperative peritoneal adhesions (PPA) are a serious problem for abdominal surgery.
An effective remedy has not been found yet.
New formulation of glycerol and sodium pentaborate may be able to solve the problem.
Method.
Female Wistar albino rats were randomly assigned into four equal groups.
The adhesion model was created on the caecum anterior wall and covered with 2 ml 0.9% NaCl, 3% glycerol, 3% sodium pentaborate, and 3% glycerol plus 3% sodium pentaborate solutions in the groups, respectively.
Two weeks later, the rats were sacrificed.
PPA were graded macroscopically and microscopically.
Results.
Total adhesion scores of the 3% glycerol + 3% sodium pentaborate group were statistically different from the other groups for macroscopic and also microscopic evaluations (p<0.001).
Conclusion.
3% glycerol plus 3% sodium pentaborate as a new formulation has preventive effects on PPA with a synergistic mechanism.
American Psychological Association (APA)
Aysan, Erhan& Sahin, Fikrettin& Catal, Ruzgar& Javadov, Mirkhaliq& Cumbul, Alev. 2020. Effects of Glycerol and Sodium Pentaborate Formulation on Prevention of Postoperative Peritoneal Adhesion Formation. Obstetrics and Gynecology International،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1203308
Modern Language Association (MLA)
Aysan, Erhan…[et al.]. Effects of Glycerol and Sodium Pentaborate Formulation on Prevention of Postoperative Peritoneal Adhesion Formation. Obstetrics and Gynecology International No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1203308
American Medical Association (AMA)
Aysan, Erhan& Sahin, Fikrettin& Catal, Ruzgar& Javadov, Mirkhaliq& Cumbul, Alev. Effects of Glycerol and Sodium Pentaborate Formulation on Prevention of Postoperative Peritoneal Adhesion Formation. Obstetrics and Gynecology International. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1203308
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1203308