Improved Biochemical Parameters in Patients Who Undergo Early Resection in Isolated Ileocaecal Crohn’s Disease
Joint Authors
Saeed, Mirzafaraz
Hullur, Hari
Salem, Amro
Ali, Abbas
Sahib, Yousif
Ashfaq, Mobeen
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
The aim of this study is to evaluate the outcome of introduction of early surgery in the course of isolated ileocecal Crohn’s disease, where there is no absolute indication of surgery.
Methods.
Observational study involving patients with isolated ileocecal Crohn’s disease who underwent early surgical resection (within one year of the presentation of the hospital).
A complete blood count, ESR, and CRP were done and compared between the preoperative value, 1st postoperative visit (3-4 weeks), and last follow-up visit.
Statistical analysis was done using Analysis of Variance (ANOVA) to compare the different figures.
Results.
There was a statistically significant increase in the hemoglobin levels between preoperative, postoperative, and long-term follow-up and a significant decrease in leukocyte count between the pre- and postoperative values (F=19.8, p<0.001 and F=8.9, p=0.002, resp.).
Similarly, the ESR and CRP values were decreased significantly at long-term follow-up (F=8.5, p=0.019 and F=8.3, p=0.013, resp.).
Conclusion.
Early surgical resection in isolated ileocaecal Crohn’s disease achieved significant biochemical improvements.
These successful results in this small number of patients indicate that early surgical intervention may provide better outcomes.
These initial results encourage larger and comparative studies of long-term results versus long-term use of biological agents.
American Psychological Association (APA)
Saeed, Mirzafaraz& Hullur, Hari& Salem, Amro& Ali, Abbas& Sahib, Yousif& Ashfaq, Mobeen. 2017. Improved Biochemical Parameters in Patients Who Undergo Early Resection in Isolated Ileocaecal Crohn’s Disease. Surgery Research and Practice،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1203502
Modern Language Association (MLA)
Saeed, Mirzafaraz…[et al.]. Improved Biochemical Parameters in Patients Who Undergo Early Resection in Isolated Ileocaecal Crohn’s Disease. Surgery Research and Practice No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1203502
American Medical Association (AMA)
Saeed, Mirzafaraz& Hullur, Hari& Salem, Amro& Ali, Abbas& Sahib, Yousif& Ashfaq, Mobeen. Improved Biochemical Parameters in Patients Who Undergo Early Resection in Isolated Ileocaecal Crohn’s Disease. Surgery Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1203502
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1203502