Dietary Cholesterol and Lipid Overload: Impact on Male Fertility
Joint Authors
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-06
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Lipid metabolic disorders due to poor eating habits are on the rise in both developed and developing countries, with a negative impact of the “Western diet” on sperm count and quality.
Dietary lipid imbalance can involve cholesterol, fatty acids, or both, under different pathophysiological conditions grouped under the term dyslipidemia.
The general feature of dyslipidemia is the development of systemic oxidative stress, a well-known deleterious factor for the quality of male gametes and associated with infertility.
Sperm are particularly rich in polyunsaturated fatty acids (PUFA), an important characteristic associated with normal sperm physiology and reproductive outcomes, but also targets of choice for oxidative thrust.
This review focuses on the effects of dietary cholesterol or different fatty acid overload on sperm composition and function in both animals and humans.
The links between oxidative stress induced by dyslipidemia and sperm dysfunction are then discussed, including possible preventive or therapeutic strategies to preserve gamete quality, longevity when stored in cryobanking, and male fertility.
American Psychological Association (APA)
Saez, Fabrice& Drevet, J. R.. 2019. Dietary Cholesterol and Lipid Overload: Impact on Male Fertility. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1203597
Modern Language Association (MLA)
Saez, Fabrice& Drevet, J. R.. Dietary Cholesterol and Lipid Overload: Impact on Male Fertility. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1203597
American Medical Association (AMA)
Saez, Fabrice& Drevet, J. R.. Dietary Cholesterol and Lipid Overload: Impact on Male Fertility. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1203597
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1203597