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Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis
Joint Authors
Gomez, Hernando D.
Su, Lian-Jiu
Zhang, Jia-Hao
Murugan, Raghavan
Hong, Xing
Xu, Dongxue
Jiang, Fan
Peng, Zhi-Yong
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-13
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Reactive oxygen species- (ROS-) induced lipid peroxidation plays a critical role in cell death including apoptosis, autophagy, and ferroptosis.
This fundamental and conserved mechanism is based on an excess of ROS which attacks biomembranes, propagates lipid peroxidation chain reactions, and subsequently induces different types of cell death.
A highly evolved sophisticated antioxidant system exists that acts to protect the cells from oxidative damage.
In this review, we discussed how ROS propagate lipid peroxidation chain reactions and how the products of lipid peroxidation initiate apoptosis and autophagy in current models.
We also discussed the mechanism of lipid peroxidation during ferroptosis, and we summarized lipid peroxidation in pathological conditions of critical illness.
We aim to bring a more global and integrative sight to know how different ROS-induced lipid peroxidation occurs among apoptosis, autophagy, and ferroptosis.
American Psychological Association (APA)
Su, Lian-Jiu& Zhang, Jia-Hao& Gomez, Hernando D.& Murugan, Raghavan& Hong, Xing& Xu, Dongxue…[et al.]. 2019. Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1203923
Modern Language Association (MLA)
Su, Lian-Jiu…[et al.]. Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1203923
American Medical Association (AMA)
Su, Lian-Jiu& Zhang, Jia-Hao& Gomez, Hernando D.& Murugan, Raghavan& Hong, Xing& Xu, Dongxue…[et al.]. Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1203923
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1203923