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The Use of Nutraceuticals to Counteract Atherosclerosis: The Role of the Notch Pathway
Joint Authors
Rizzo, Paola
Campo, Gianluca
Calabria, D.
Aquila, Giorgio
Marracino, Luisa
Martino, Valeria
Caliceti, Cristiana
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-30, 30 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-02
Country of Publication
Egypt
No. of Pages
30
Main Subjects
Abstract EN
Despite the currently available pharmacotherapies, today, thirty percent of worldwide deaths are due to cardiovascular diseases (CVDs), whose primary cause is atherosclerosis, an inflammatory disorder characterized by the buildup of lipid deposits on the inside of arteries.
Multiple cellular signaling pathways have been shown to be involved in the processes underlying atherosclerosis, and evidence has been accumulating for the crucial role of Notch receptors in regulating the functions of the diverse cell types involved in atherosclerosis onset and progression.
Several classes of nutraceuticals have potential benefits for the prevention and treatment of atherosclerosis and CVDs, some of which could in part be due to their ability to modulate the Notch pathway.
In this review, we summarize the current state of knowledge on the role of Notch in vascular health and its modulation by nutraceuticals for the prevention of atherosclerosis and/or treatment of related CVDs.
American Psychological Association (APA)
Aquila, Giorgio& Marracino, Luisa& Martino, Valeria& Calabria, D.& Campo, Gianluca& Caliceti, Cristiana…[et al.]. 2019. The Use of Nutraceuticals to Counteract Atherosclerosis: The Role of the Notch Pathway. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-30.
https://search.emarefa.net/detail/BIM-1204178
Modern Language Association (MLA)
Aquila, Giorgio…[et al.]. The Use of Nutraceuticals to Counteract Atherosclerosis: The Role of the Notch Pathway. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-30.
https://search.emarefa.net/detail/BIM-1204178
American Medical Association (AMA)
Aquila, Giorgio& Marracino, Luisa& Martino, Valeria& Calabria, D.& Campo, Gianluca& Caliceti, Cristiana…[et al.]. The Use of Nutraceuticals to Counteract Atherosclerosis: The Role of the Notch Pathway. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-30.
https://search.emarefa.net/detail/BIM-1204178
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204178