Beneficial Effects of Citrus Flavonoids on Cardiovascular and Metabolic Health
Joint Authors
Mahmoud, Ayman M.
Hussein, Omnia E.
Sandhu, Mansur A.
Hernández Bautista, Rene J.
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-10
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
The prevalence of cardiovascular disease (CVD) is increasing over time.
CVD is a comorbidity in diabetes and contributes to premature death.
Citrus flavonoids possess several biological activities and have emerged as efficient therapeutics for the treatment of CVD.
Citrus flavonoids scavenge free radicals, improve glucose tolerance and insulin sensitivity, modulate lipid metabolism and adipocyte differentiation, suppress inflammation and apoptosis, and improve endothelial dysfunction.
The intake of citrus flavonoids has been associated with improved cardiovascular outcomes.
Although citrus flavonoids exerted multiple beneficial effects, their mechanisms of action are not completely established.
In this review, we summarized recent findings and advances in understanding the mechanisms underlying the protective effects of citrus flavonoids against oxidative stress, inflammation, diabetes, dyslipidemia, endothelial dysfunction, and atherosclerosis.
Further studies and clinical trials to assess the efficacy and to explore the underlying mechanism(s) of action of citrus flavonoids are recommended.
American Psychological Association (APA)
Mahmoud, Ayman M.& Hernández Bautista, Rene J.& Sandhu, Mansur A.& Hussein, Omnia E.. 2019. Beneficial Effects of Citrus Flavonoids on Cardiovascular and Metabolic Health. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-19.
https://search.emarefa.net/detail/BIM-1204182
Modern Language Association (MLA)
Mahmoud, Ayman M.…[et al.]. Beneficial Effects of Citrus Flavonoids on Cardiovascular and Metabolic Health. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-19.
https://search.emarefa.net/detail/BIM-1204182
American Medical Association (AMA)
Mahmoud, Ayman M.& Hernández Bautista, Rene J.& Sandhu, Mansur A.& Hussein, Omnia E.. Beneficial Effects of Citrus Flavonoids on Cardiovascular and Metabolic Health. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-19.
https://search.emarefa.net/detail/BIM-1204182
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204182