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lncRNAs Regulate Innate Immune Responses and Their Roles in Macrophage Polarization
Joint Authors
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The innate immune system is the first line of defense against microbial pathogens.
The activated innate immune system plays important roles in eliciting antimicrobial defenses.
Despite the benefits of innate immune responses, excessive inflammation will cause host damage.
Thus, tight regulation of these processes is required for the maintenance of immune homeostasis.
Recently, a new class of long noncoding RNAs (lncRNAs) has emerged as important regulators in many physiological and pathological processes.
Dysregulated lncRNAs have been found to be associated with excessive or uncontrolled inflammation.
In this brief review, we summarize the roles of functional lncRNAs in regulating innate immune responses.
We also discuss the roles of lncRNAs in macrophage polarization, an important molecular event in the innate immune responses.
American Psychological Association (APA)
Wang, Zhen& Zheng, Ying. 2018. lncRNAs Regulate Innate Immune Responses and Their Roles in Macrophage Polarization. Mediators of Inflammation،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1204263
Modern Language Association (MLA)
Wang, Zhen& Zheng, Ying. lncRNAs Regulate Innate Immune Responses and Their Roles in Macrophage Polarization. Mediators of Inflammation No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1204263
American Medical Association (AMA)
Wang, Zhen& Zheng, Ying. lncRNAs Regulate Innate Immune Responses and Their Roles in Macrophage Polarization. Mediators of Inflammation. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1204263
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204263