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Gut Microbiota in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: Current Applications and Future Perspectives
Joint Authors
Zhu, Jie
Jin, Tao
Cui, Li
Lang, Yue
Chu, Fengna
Shen, Donghui
Shi, Mingchao
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-02
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
The gut environment and gut microbiome dysbiosis have been demonstrated to significantly influence a range of disorders in humans, including obesity, diabetes, rheumatoid arthritis, and multiple sclerosis (MS).
MS is an autoimmune disease affecting the central nervous system (CNS).
The etiology of MS is not clear, and it should involve both genetic and extrinsic factors.
The extrinsic factors responsible for predisposition to MS remain elusive.
Recent studies on MS and its animal model, experimental autoimmune encephalomyelitis (EAE), have found that gastrointestinal microbiota may play an important role in the pathogenesis of MS/EAE.
Thus, gut microbiome adjustment may be a future direction of treatment in MS.
In this review, we discuss the characteristics of the gut microbiota, the connection between the brain and the gut, and the changes in gut microbiota in MS/EAE, and we explore the possibility of applying microbiota therapies in patients with MS.
American Psychological Association (APA)
Chu, Fengna& Shi, Mingchao& Lang, Yue& Shen, Donghui& Jin, Tao& Zhu, Jie…[et al.]. 2018. Gut Microbiota in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: Current Applications and Future Perspectives. Mediators of Inflammation،Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1204287
Modern Language Association (MLA)
Chu, Fengna…[et al.]. Gut Microbiota in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: Current Applications and Future Perspectives. Mediators of Inflammation No. 2018 (2018), pp.1-17.
https://search.emarefa.net/detail/BIM-1204287
American Medical Association (AMA)
Chu, Fengna& Shi, Mingchao& Lang, Yue& Shen, Donghui& Jin, Tao& Zhu, Jie…[et al.]. Gut Microbiota in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: Current Applications and Future Perspectives. Mediators of Inflammation. 2018. Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1204287
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204287