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Oxidative Stress in Radiation-Induced Cardiotoxicity
Joint Authors
Hong, Lang
Liang, Shao
Ping, Zhang
Peng, Yang
Xinyong, Cai
Zhiyi, Zeng
Xiaocheng, Wu
Hong, Zeng
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-02
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
There is a distinct increase in the risk of heart disease in people exposed to ionizing radiation (IR).
Radiation-induced heart disease (RIHD) is one of the adverse side effects when people are exposed to ionizing radiation.
IR may come from various forms, such as diagnostic imaging, radiotherapy for cancer treatment, nuclear disasters, and accidents.
However, RIHD was mainly observed after radiotherapy for chest malignant tumors, especially left breast cancer.
Radiation therapy (RT) has become one of the main ways to treat all kinds of cancer, which is used to reduce the recurrence of cancer and improve the survival rate of patients.
The potential cause of radiation-induced cardiotoxicity is unclear, but it may be relevant to oxidative stress.
Oxidative stress, an accumulation of reactive oxygen species (ROS), disrupts intracellular homeostasis through chemical modification and damages proteins, lipids, and DNA; therefore, it results in a series of related pathophysiological changes.
The purpose of this review was to summarise the studies of oxidative stress in radiotherapy-induced cardiotoxicity and provide prevention and treatment methods to reduce cardiac damage.
American Psychological Association (APA)
Ping, Zhang& Peng, Yang& Hong, Lang& Xinyong, Cai& Zhiyi, Zeng& Xiaocheng, Wu…[et al.]. 2020. Oxidative Stress in Radiation-Induced Cardiotoxicity. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1204292
Modern Language Association (MLA)
Ping, Zhang…[et al.]. Oxidative Stress in Radiation-Induced Cardiotoxicity. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-15.
https://search.emarefa.net/detail/BIM-1204292
American Medical Association (AMA)
Ping, Zhang& Peng, Yang& Hong, Lang& Xinyong, Cai& Zhiyi, Zeng& Xiaocheng, Wu…[et al.]. Oxidative Stress in Radiation-Induced Cardiotoxicity. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1204292
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204292